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Angiodysplasia of the Colon

(Colonic Angiodysplasia, Arteriovenous Malformations [AVM] of the Colon)

Definition

Angiodysplasia of the colon occurs when blood vessels in the colon enlarge. They may become fragile and result in occasional bleeding in the gastrointestinal (GI) tract.
Normal Anatomy of the Intestines
Normal Anatomy of the Large and Small Intestine
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Causes

Angiodysplasia of the colon is caused by dilated connections between veins and capillaries or arteries in the large intestine (colon).

Risk Factors

Factors that may increase your risk of angiodysplasia of the colon include:

Symptoms

Symptoms of angiodysplasia of the colon may include:

Diagnosis

Your doctor will ask about your symptoms and medical history. A physical exam will be done.
Your bodily fluids and waste may be tested. This can be done with:
Your internal structures may need to be viewed. This can be done with:

Treatment

Talk with your doctor about the best treatment plan for you. Treatment may not be necessary, since about 90% of cases of angiodysplasia of the colon stop bleeding on their own. Treatment options include the following:

Colonoscopy

Your doctor can often treat tissues with heat to seal bleeding blood vessels during a colonoscopy.

Angiography

The blood supply to the bleeding area can be clotted through angiography.

Medical Therapy

Hormonal therapy with estrogen can be helpful for some causes.
Medications called somatostatin analogs may be used to prevent bleeding in some people.

Surgery

Surgery to remove the affected area of the colon may sometimes be necessary.

Prevention

There are no current guidelines to prevent angiodysplasia of the colon.

RESOURCES

AGS Foundation for Health in Aging http://www.healthinaging.org

National Digestive Diseases Information Clearinghouse http://digestive.niddk.nih.gov

CANADIAN RESOURCES

Canadian Association of Gastroenterology http://www.cag-acg.org

Canadian Digestive Health Foundation http://www.cdhf.ca

References

American Gastroenterological Association. AGA guideline: Evaluation and management of occult and obscure gastrointestinal bleeding. Gastroenterology. 2000;118:197.

Gastrointestinal angiodysplasia. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated June 2, 2014. Accessed June 16, 2014.

6/19/2014 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed: Jackson CS, Gerson LB. Management of gastrointestinal angiodysplastic lesions (GIADs): A systematic review and meta-analysis. Am J Gastroenterol. 2014;109(4):474-483.

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