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Intraventricular Hemorrhage of Infancy

(IVH; Subependymal Germinal Matrix Hemorrhage; Early-onset Germinal Matrix Hemorrhage; EGMH; Periventricular-Intraventricular Hemorrhage; PIVH)

Definition

Intraventricular hemorrhage (IVH) is bleeding into the spaces of a baby’s brain. IVH is most common in premature babies.
IVH may cause damage to brain tissue and lead to long-term development problems.
Ventricles of the Brain
Ventricles of the Brain
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Causes

IVH is caused by the rupture of immature or fragile blood vessels in the brain. It is not clear why this happens but changes in blood pressure may play a role.

Risk Factors

Factors that increase your baby’s chance of developing IVH include:

Symptoms

It often occurs in the first 48 hours after birth. In many cases, there are no visible signs of IVH. Symptoms that may occur include:

Diagnosis

A physical exam will be done. The doctor will look for any signs of a brain injury.
An ultrasound will be used to make images of the brain structures, blood vessels, and blood flow in the brain.
Other tests, like blood tests, may be done to look for anemia and causes of the bleeding.

Treatment

In most cases, the bleeding gradually stops. Treatment options include:
Certain procedures or surgery may need to be done to relieve pressure in the brain:

Prevention

If you are at risk of having a premature baby, you may be given medication to decrease the chance of IVH.

RESOURCES

American Academy of Neurology http://www.aan.com

Healthy Children—American Academy of Pediatrics http://healthychildren.org

CANADIAN RESOURCES

Canadian Pediatric Society http://www.cps.ca

Health Canada http://www.hc-sc.gc.ca

References

Ballabh P. Intraventricular hemorrhage in premature infants: mechanism of disease. Pediatr Res. 2010;67(1):1-8.

Cunningham FG, Leveno KJ, Bloom SL, et al. Diseases and injuries of the fetus and newborn. In: Obstetrics. 23rd ed. New York, NY: McGraw-Hill Books; 2010:605-645.

Intraventricular hemorrhage. Boston Children's Hospital website. Available at: http://www.childrenshospital.org/health-topics/conditions/intraventricular-hemorrhage. Accessed June 24, 2013.

Intraventricular hemorrhage of infancy. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated March 24, 2011. Accessed August 12, 2014.

Fowlie PW, Davis PG, McGuire W. Prophylactic intravenous indomethacin for preventing mortality and morbidity in preterm infants. Cochrane Database of Syst Rev 2010;7:CD000174.

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