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(Dry Gangrene; Gas Gangrene; Organ or Tissue Death; Wet Gangrene)


Gangrene is the progressive death of body tissue resulting from a lack of blood supply. When the blood supply is cut off, the tissue does not get enough oxygen and begins to die.
Gangrene can be internal or external. The two most common types of gangrene are:
A rare wet type, called gas gangrene, develops from specific bacteria deep inside the body. Gas gangrene can be a result of surgery or trauma.


Gangrene is caused by infection or a reduced blood supply to tissues.

Risk Factors

Gangrene is more common in older adults.
Factors that may increase your chance of developing gangrene include:


External gangrene may cause:
Internal gangrene may cause:
If the gangrene is widespread, sepsis can occur.
Gangrene of the Foot
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You will be asked about your symptoms and medical history. A physical exam will be done.
Your bodily fluids may be tested. This can be done with: :
Images may be taken of your bodily structures. This can be done with:


Treatment of gangrene includes:


To help reduce your chance of getting gangrene, take these steps:


American Diabetes Association

Family Doctor—American Academy of Family Physicians


Canadian Diabetes Association

Health Canada


A quick summary of the 6 types of necrosis. Pathology Student website. Available at: Accessed September 29, 2014.

Fujiwara Y, Kishida K, et al. Beneficial effects of foot care nursing for people with diabetes mellitus: an uncontrolled before and after intervention study. J Adv Nurs. 2011;67(9):1952-1962.

Gangrene. NHS Choices website. Available at: Accessed January 27, 2014.

Gas gangrene. EBSCO DynaMed website. Available at: Updated July 25, 2014. Accessed September 29, 2014.

Sepsis in adults. EBSCO DynaMed website. Available at: Updated July 25, 2014. Accessed September 29, 2014.

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